Restylane FAQs: Cost, Results, Side Effects & More

BY: Editors |Dec 19, 2018

If you've kept up with pop-culture or beauty trends in the past few years then you know that "Kylie Jenner lips" are a thing. A really big thing. The Instagram and reality TV star's noticeably plumper lips took us by storm back in 2015, and they helped bring the quest for perfection through the use of cosmetic fillers into the mainstream.

One way to enhance your lips, smooth out wrinkles, or add fullness to the face is by using Restylane, an injectable dermal filler. We tapped into the knowledge of Dr. Wafik A. Hanna, who specializes in facial cosmetic surgery at his Chicagoland practice, to get the low-down on this treatment.

Choose one of the questions below to learn more about Restylane.

Woman with full lips with Chicago backdrop

What is Restylane?

According to Dr. Hanna, Restylane is an FDA-approved soft-tissue filler designed to plump up lips and smooth facial wrinkles and folds.

Dr. Hanna says that Restylane was "the first cosmetic dermal filler made of sugar-based hyaluronic acid. Hyaluronic acid is a natural substance that already exists in the human body."

Read more about hyaluronic acid and how else you can incorporate it into your beauty routine.

How does Restylane work?

Once Restylane is injected into the skin, it adds temporary support to the skin's structure and replaces lost volume. The result is smoother wrinkles and fuller lips. Restylane also helps stimulate the production of more collagen.

What type of Restylane do I need?

Your provider will decide which one is best for you. However, these are the main types of Restylane:

RESTYLANE Plumps up nasolabial folds Up to 18 months According to Dr. Hanna, when Restylane is used for the first time, the average results can last anywhere from 6 to 9 months. With a follow-up treatment, you can expect results to last up to 18 months.
RESTYLANE SILK Plumps lips and smoothes wrinkles around the mouth Approximately 6 months Uses smaller, smoother hyaluronic acid particles than other Restylane products
RESTYLANE LYFT Treats moderate to severe facial folds. Adds volume to the back of the hands and to cheeks. And corrects age-related midface contour deficiencies.
  1. Cheeks: up to 12 months
  2. Back of the hands: up to 6 months
  3. Facial wrinkles and folds: up to 6 months
First hyaluronic acid filler approved by the FDA to be used in the hands. Radiesse, a calcium hydroxylapatite filler, is also approved to be used in the hands.
RESTYLANE REFYNE Softens facial wrinkles and folds (such as nasolabial folds and marionette lines) Up to 12 months A little bit thinner, better for more superficial lines
RESTYLANE DEFYNE Softens deeper  facial wrinkles and folds (such as nasolabial folds and marionette lines) Up to 12 months A little bit thicker, better for deeper lines

How much Restylane do I need?

According to the manufacturer, patients typically achieve their desired results after one or two sessions. How much you need exactly depends on things like the treatment area, your age, and the depth of your wrinkles. Your doctor can tell you how many sessions you'll need to achieve a good result during your consultation.

If you buy one of our deals and your consultation reveals that you’ll need more sessions than is satisfactory, we will honor your refund request.

Your second session usually requires less Restylane.

According to Dr. Hanna, on average, only half the amount of Restylane used during the initial treatment is needed at the follow-up treatment. That’s because more collagen is formed in most patients who repeatedly get dermal fillers over time—which means fewer injections are needed for upkeep and maintenance.

How much time do I wait between Restylane treatments?

To get results for up to 18 months, you likely will only need a follow-up treatment 4.5 or 9 months after your initial treatment.

How soon can I see results?

Restylane instantly adds volume when it's injected, so results are noticeable immediately after a treatment. Final results can be seen 1–2 weeks after any potential swelling or bruising has had time to subside.

How much does Restylane cost?

The usual rate for a Restylane treatment is somewhere between $400–$800 per syringe. But if use our site, you should consistently find Restylane treatments below $500 per syringe and as low as $375 per syringe.

Click here to see deals on Restylane treatments near you.

Woman with full lips

Am I eligible for Restylane?

Most adults are eligible for Restylane (the manufacturer doesn't recommend it for anyone younger than 22).

According to the manufacturer, you should not get Restylane if you:

  • Are pregnant or breastfeeding
  • Have recently used drugs that thin the blood or prevent clotting
  • Have had previous bad allergies, particularly to microorganisms known as gram-positive bacteria
  • Have serious allergies to drugs that have previously required in-hospital treatment
  • Have bleeding disorders
  • Have a known allergy to lidocaine

Inform your doctor if you:

  • Have any history of scarring, particularly thick and stiff scars, or any pigmentation disorders. These are potential side effects with any type of hyaluronic acid filler.
  • Are planning to get any laser treatments or chemical peels after your injection, as there is a possible risk of inflammation at the treatment site
  • Have a skin injury near the site of injection
  • Are on any medications that decrease your body’s immune response (immunosuppressive therapy)
  • Are using any “blood thinners” such as aspirin, warfarin, or any other medications that affect bleeding
  • Have diseases, injuries, or disabilities of the hand

You should wait to get Restylane if you have skin sores, pimples, rashes, hives, cysts, or infections at the treatment site. Use of product in these areas could delay healing or make your skin problems worse.

Are there any side effects?

You might experience temporary injection-site reactions, such as pain, itching, redness, swelling, and bruising. A headache is also possible, as is impaired hand function.

The side effects normally last fewer than 7 days in nasolabial folds and fewer than 14 days in lips.

Serious but rare side effects include delayed onset infections, recurrence of herpetic eruptions, and superficial necrosis at the injection site.

Another risk is unintentional injection into a blood vessel. The chances of this happening are very small, but if it does happen, the complications can be serious, and may be permanent. These complications, which have been reported for facial injections, can include vision abnormalities, blindness, stroke, temporary scabs, or permanent scarring of the skin.

As with all skin injection procedures, there is a risk of infection.

Read all of the safety considerations for Restylane here.


The information contained in this article is from an interview with Dr. Wafik A. Hanna and Restylane’s website.

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