Bella capsules contain Topiramate 15mg, Bupropion 65mg, Naltrexone 8mg, Methylcobalamin (B12) 1mg, and Phentermine 20mg. These individually FDA-approved medications are used off-label together for weight loss with fantastic results.

Topiramate (FDA-approved as Topamax) has been shown to cause weight loss when used for seizure control and migraine prevention. While not individually approved by the FDA specifically for weight loss, it makes weight loss easier by reducing leptin (the hunger hormone) and cortisol, which is known to cause belly fat gain.

Bupropion (FDA-approved as Wellbutrin) increases levels of dopamine and norepinephrine, which play a role in satiety. For many people with overweight or obesity, this helps reduce cravings and overall food intake.

Naltrexone helps normalize metabolism, matching appetite to resting energy expenditures, and modulates cellular resistance to insulin. It is a μ-opioid receptor antagonist that may reduce food consumption by blocking β-endorphin action and preventing autoinhibition of pro-opiomelanocortin neurons.

Methylcobalamin B12 works by converting food into fuel to keep the body running smoothly. It is associated with weight loss due to its ability to boost metabolism and provide lasting energy.

Phentermine (FDA-approved as Adipex-P, Lomaira) is a prescription medicine used to lessen appetite and help you feel full longer. Under a controlled environment, users could lose up to 5% of total body weight within 8–12 weeks (equivalent to 1–2% body weight reduction per week).